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High cholesterol is one of the most common and manageable risk factors for heart disease. Millions of adults are prescribed cholesterol-lowering drugs to reduce low-density lipoprotein (LDL) cholesterol, support heart health, and prevent serious events such as heart attack and stroke. With many treatment options available, it can be challenging to understand how different medications work and which ones may be right for you.

In this guide, SaveHealth, a prescription discount/savings card website, explains the most common medications for high cholesterol, how they compare, and what to know about safety and side effects. It is designed for people who have been diagnosed with high cholesterol or are exploring treatment options.

Understanding high cholesterol and treatment goals

Cholesterol is a waxy substance found in the blood. The body needs some cholesterol to function, but too much LDL cholesterol can build up in the arteries, causing a blockage, thereby increasing cardiovascular risk.

Treatment goals often include:

1. Lowering LDL cholesterol.
2. Improving overall lipid balance.
3. Reducing long-term cardiovascular risk.
4. Supporting lifestyle changes such as diet and exercise.

Doctors choose medications based on cholesterol levels, personal risk factors, and how well a patient tolerates certain drugs.

Main classes of cholesterol-lowering drugs

Before reviewing individual prescriptions, it helps to understand the major categories.

Common cholesterol-lowering drug classes include:

1. Statins, which reduce cholesterol production in the liver.
2. Cholesterol absorption inhibitors, which reduce cholesterol absorption from the small intestine.
3. Bile acid sequestrants, which bind cholesterol in the intestines of the digestive tract.
4. PCSK9 inhibitors and siRNA therapies regulate cholesterol production in the liver, which significantly helps lower LDL.
5. ATP citrate lyase inhibitors (also known as ACL inhibitors) reduce cholesterol synthesis in a different pathway.
6. Combination therapies, which use two mechanisms in one pill.

Each class plays a different role in LDL cholesterol treatment.

Statin medications for high cholesterol

Statins are the most widely prescribed cholesterol medications. They are proven to reduce LDL cholesterol and lower the risk of heart attack and stroke.

Common statin medications for high cholesterol include:

1. Atorvastatin, generic for the trade name Lipitor.
2. Simvastatin, generic for the trade name Zocor.
3. Lovastatin, generic for the trade name Mevacor.
4. Fluvastatin, generic

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Each year, winter weather brings several challenges to drivers—one of the most notable is frozen precipitation. Snow, sleet, and freezing rain each pose unique hazards, including reduced visibility, poor traction, and unpredictable road conditions. Unlike general winter driving concerns, like low temperatures and early-onset darkness, these forms of cold-weather precipitation directly affect how your vehicle interacts with the road.

In this guide, Husky Liners breaks down the main differences between snow, sleet, and freezing rain. Learn what to do—and what to avoid—when you encounter any of these conditions while on the road this winter.

Snow vs. Sleet vs. Freezing Rain: Main Differences

While snow, sleet, and freezing rain may look similar from inside your vehicle, they behave significantly differently on the road. Understanding these differences is the first step toward adjusting your driving habits appropriately.

For more information on what makes these weather conditions different, check out the table below.

Husky Liners

How to Drive in Snow

Snow is the most familiar and easily navigable type of winter precipitation, but that doesn’t mean it should be taken lightly. Even light snow can significantly reduce visibility, while heavy snow accumulation can reduce your tire’s ability to maintain grip. When tightly packed, snow can also behave similarly to ice.

6 Do’s of Driving in the Snow

Driving in the snow requires several strategic changes to driving habits to ensure safety. These include:

• DO increase following distance.
• DO drive at reduced speeds.
• DO accelerate and brake gradually.
• DO keep headlights on at all times of day.
• DO clear snow from your vehicle before driving.
• DO use winter tires. 

5 Don’ts of Driving in the Snow

Additionally, there are some driving habits you should avoid in the snow, as these moves can lead to loss of control or accidents. When the snow begins to fall, avoid the following behaviors behind the wheel:

• DON’T use cruise control.
• DON’T make sudden steering inputs.
• DON’T follow snowplows dangerously closely.
• DON’T assume that 4WD or AWD eliminates the risk of losing traction.
• DON’T overcorrect while sliding—turn into the slide or let the wheel free turn until the vehicle comes to a stop.

Sleet creates a uniquely hazardous situation due to the erratic, unpredictable

Kevin Dietsch // Getty Images

Could the new federal tax-credit scholarship program pay for summer school or tutoring for public school students? Could it help homeschool families, microschools, and after-school enrichment programs alike?

Or will most of the money mirror voucher programs and flow through large established scholarship groups for private school tuition?

The race is on to shape a program that could become one of the largest federal investments in K-12 education and fuel a dramatic expansion of private school choice, Chalkbeat reports. The Treasury Department fired the starter’s pistol right before Thanksgiving when it posted a request for comments on how to implement the new tax credit, which passed this summer as part of the One Big Beautiful Bill.

Requesting comment before developing draft rules is the first step in a process that ultimately will determine how much authority states have to put their own stamp on the program, how attractive it is for nonprofits, and how much flexibility families will have.

Treasury Department rules could influence whether some governors choose to have their states participate at all. The Democratic governors of Colorado and North Carolina already plan to opt their states in. Many others have said they’re waiting on federal guidance before they decide.

But on one of the key questions — can governors put restrictions on scholarship-granting organizations, such as requiring that they serve only low-income families or prohibiting them from discriminating against LGBTQ students? The answer may already be no.

The request for comment indicates that Treasury expects to require participating states to include all organizations that meet the bare-bones statutory requirements, such as being a federally recognized nonprofit and serving more than 10 students who don’t all attend the same school.

“It’s really a take it or leave it scheme,” said Rachel Canter, director of education policy for the Progressive Policy Institute, a think tank.

The law doesn’t define “school,” and the Treasury Department has not explicitly asked for feedback on how it should be defined. That could lead to more questions: Could scholarships be used to cover preschool tuition? What about microschools or students who are homeschooled? School choice advocates want those students to have access to funds raised through the tax credit, but some are wary of creating a federal definition of school through the rule-making process.

People who believe in usi

Courtesy of Emory University

As the U.S. public health system weighs how to integrate artificial intelligence, an Emory University lab is patenting new ideas for precision medicine that its leader says could bring AI research into practical use — quickly and with nuance.

Professor Anant Madabhushi’s work covers AI options for detecting and treating a dizzying range of diseases, from cancer to HIV to cardiovascular disease, in countries from China to Tanzania to Brazil.

The bioengineer’s upbringing in Mumbai, India, and work with researchers around the world have driven his focus on finding uses for AI to save money, time, and resources in public health and health care.

Madabhushi holds more than 225 issued or pending patents and has headed the Empathetic AI for Health Institute at Emory since 2023. He’s also co-founded several companies focused on AI in health.

The U.S. Department of Health and Human Services announced on Dec. 4 an intention to incorporate AI into public health.

Artificial intelligence could have major public health benefits across the world, including the rural United States, Madabhushi said. But he’s concerned the United States is falling behind in the large-cohort studies needed to fuel AI’s promise.

“The necessity of these technologies, frugal and opportunistic, have implications not just in the Global South, but also in rural America,” he said. “We really owe it to Americans to be able to do whatever we can, particularly in this time of health care costs and some of the challenges with access.”

Healthbeat shares seven takeaways from a recent conversation with Madabhushi.

• Artificial intelligence will not replace clinicians.

“In reality, the real value lies in augmenting clinical decision-making, reducing variability, and expanding access — especially where clinical expertise is limited,” Madabhushi said. That includes parts of the world with limited resources, whether that’s his native India or rural Georgia.

• Artificial intelligence has the power to transform lives and health systems, but the breakthroughs aren’t “plug-and-play.”

“In truth, they require careful validation, bias mitigation, regulatory oversight, and thoughtful deployment to ensure they actually help patients rather than introduce new inequities,” Madabhushi said.

He pointed to the example of a cancer center in India that sees about 1 million patients a year.

“Whatever technology you bring into play not only has to be able to deliver accurate insights, it also has to be done in a way that doesn’t add time to the system,” Madabhushi said. “You can’t add more complexity. You can’t add more seconds to the diagnosis, to the clinical workflow.”

With 1 million patients a year, just one second added to the workflow means “suddenly you’re talking about some serious amount of time.”

• Eyes are diagnostic windows to health.

Using AI, eyes

Por Kit Maher, CNN

La Casa Blanca dijo este martes que está “analizando una variedad de opciones” para adquirir Groenlandia, y señaló que el uso de las Fuerzas Armadas de Estados Unidos no está descartado.

“El presidente Trump ha dejado claro que la adquisición de Groenlandia es una prioridad de seguridad nacional para Estados Unidos y es fundamental para disuadir a nuestros adversarios en la región ártica. El presidente y su equipo están evaluando diversas alternativas para alcanzar este importante objetivo de política exterior y, por supuesto, recurrir a las Fuerzas Armadas estadounidenses siempre es una opción disponible para el comandante en jefe”, dijo la secretaria de prensa de la Casa Blanca, Karoline Leavitt, en un comunicado a CNN.

El presidente Donald Trump ha mostrado en los últimos días un renovado interés en adquirir este territorio danés, lo que provocó una declaración de apoyo a Dinamarca por parte de líderes europeos este mismo martes.

El principal asesor de la Casa Blanca, Stephen Miller, dijo a Jake Tapper de CNN el lunes que nadie enfrentaría militarmente a Estados Unidos “por el futuro de Groenlandia”.

Noticia en desarrollo…

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