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After more than a decade without major breakthroughs in anxiety medication, several promising treatments are now moving through clinical trials. These investigational options use new delivery systems, novel mechanisms or compounds different from traditional selective serotonin reuptake inhibitors (SSRIs) and benzodiazepines. If approved, LifeStance Health highlights that they may change how clinicians approach conditions such as generalized anxiety disorder (GAD), social anxiety disorder and anxiety that occurs alongside depression.

Below is a look at several anxiety-related medications expected to reach important trial milestones or potential FDA consideration in 2026.

MM120: A breakthrough approach using psychedelic science

MM120 is an investigational treatment being developed by MindMed for generalized anxiety disorder (GAD). It uses a small, precisely controlled dose of a psychedelic compound (a form of LSD) that dissolves on the tongue.

In a Phase 2 study, participants reported improvement in anxiety symptoms after a single dose, with potential benefits observed for up to 12 weeks.

MM120 is now in Phase 3 of clinical trials, which are evaluating its effectiveness and safety. Researchers conducting these trials are measuring changes in anxiety symptoms over 12 weeks and following participants for up to one year to assess long-term outcomes.

If successful, MM120 may become the first psychedelic-derived treatment the FDA has approved for GAD, offering a potentially fast-acting and long-lasting option for individuals who have not had success with existing treatments.

GlyphAllo: A novel pathway for depression with anxious distress

Seaport Therapeutics is developing Glyph Allopregnanolone (GlyphAllo) to treat major depressive disorder (MDD), including depression that occurs with significant anxiety symptoms.

The body naturally produces allopregnanolone, a hormone-like substance that helps the brain manage stress and regulate mood. Historically, allopregnanolone has only been available as an intravenous (IV) injection because the body does not absorb it well when taken orally.

GlyphAllo is designed to improve oral absorption so that more of the medication reaches the brain. It remains in clinical trials, and researchers are studying whether GlyphAllo may provide a new treatment option for depression with anxious distress.

Fasedienol: A nasal spray for social anxiety disorder

Meanwhile, Vistage

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Teens with depression have to navigate the challenges of living with a mood disorder, along with the usual academic and social pressures of high school. A depression diagnosis may be unsettling, but there are several different ways to treat depression in teens — including some that are low-risk and highly effective. Being the parent or loved one of a teen with depression has its own challenges — help and resources are available for you, too.

Depression can affect people of any age — including teens. In fact, the National Institute of Mental Health estimates that 5 million, or 20.1%, of adolescents aged 12 to 17 in the United States have had at least one major depressive episode. Yet despite depression in teenagers being quite prevalent, only 40.6% of teens with a major depressive episode receive treatment for the mental health condition.

If you’re looking for a clear, comprehensive, and compassionate guide to treatments for teen depression, you’ve come to the right place. Radial explores what works, what to expect, and how families can help.

What is teen depression?

Depression in teens is a serious mood disorder that causes ongoing feelings of sadness, emptiness, or hopelessness and a loss of interest in things someone used to enjoy. While it’s normal to be sad for a few days, depression can last for months or years.

Teen depression statistics vary, but globally, it’s estimated that 1.3% of adolescents aged 10–14 years, and 3.4% of 15–19-year-olds are currently experiencing a serious depression, according to the World Health Organization. “In any given year, a teen is more likely to have disabling depression than catching the flu,” says Eugene Grudnikoff, MD, a child and adolescent psychiatrist practicing in New York.

Radial

Symptoms of teen depression

Teens with depression have one or more of these symptoms most of the time:

• Sadness
• Feeling of emptiness
• Hopelessness
• Being angry, irritable, or fr

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At the end of the year, music lovers get their Spotify Wrapped reports, summarizing all the tunes they listened to in 2025.

What if you analyzed your money goals in the same way?

In other words, as 2026 begins, it is a great time to review the financial milestones you were striving for this year — and to use those results to chart a better path this year.

As it happens, Current, a consumer fintech banking platform, knows exactly what money goals people were aiming for in 2025, thanks to a survey from financial information site Bankrate. The top one, by a significant margin: Paying down debt, identified by 21% of people. Other top responses included saving more money for emergencies and getting a higher-paying job.

Of course, life requires people to juggle many different financial aims at once. The real challenge is finding the right balance, so you can make progress on multiple goals in 2026.

“The number one task is to identify your top priorities,” says Mark Hamrick, Bankrate’s senior economic analyst. “It’s not unlike putting together a puzzle. Once you get an idea of what your puzzle pieces are and how they fit together, that’s part of the process of doing the work and attaining your financial goals over a lifetime.”

So looking back, how did Americans fare in 2025? Here’s a roundup of people’s top money goals.

Paying down debt. It’s not surprising that this was number one on everybody’s collective wishlist, considering Americans are struggling with it so mightily.

Look at the latest numbers from the New York Fed: Total household debt stood at a record $18.59 trillion in this year’s third quarter, comprising everything from mortgages to credit cards to auto loans to student debt. Anything households can do to reduce that burden — and the interest being paid on it — is a sound strategy for the future.

Saving for emergencies. If your budget has little margin for error, and you are hit with sudden expenses, “that’s when things start to get dicey,” says Hamrick. It forces you into a debt spiral that could potentially end in bankruptcy.

That’s why a pot of emergency savings is so critical — between three and six months’ worth of expenses, suggests Hamrick, to help you get through any rough patches like layoffs or medical crises. “More is always better.”

Rather than having that cash sit and earn nothing, make sure to give it a boost in a higher-yielding account.

Getting a higher-paying job or an additional source of income. Affordability is the watchword of the day, since consumer costs have been rising for years — spiking during the COVID-19 pandemic, and still proving stickily high, thanks to factors like tariffs. (Inflation is currently around Read more

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CheapInsurance.com compiled statistics on gas prices in the U.S. using data from AAA. Gas prices are current as of January 5.

U.S. by the numbers
– Gas current price: $2.81
– Week change: -$0.01 (-0.5%)
– Year change: -$0.25 (-8.1%)
– Historical expensive gas price: $5.02 (6/14/22)

– Diesel current price: $3.52
– Week change: -$0.03 (-0.9%)
– Year change: +$0.00 (+0.1%)
– Historical expensive diesel price: $5.82 (6/19/22)

Metros with the least expensive gas
#1. Des Moines, IA: $2.00
#2. Casper, WY: $2.01
#3. Columbus, NE: $2.12

Read on to see which metros have the most expensive gas prices.

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#5. San Luis Obispo-Atascadero-Paso Robles, CA

– Regular gas price: $4.46

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#4. San Diego, CA

– Regular gas price: $4.46

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#3. Napa, CA

– Regular gas price: $4.46

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#2. Hilo, HI

– Regular gas price: $4.58

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#1. Lihue (Kauai), HI

– Regular gas price: $4.96

This story was produced by CheapInsurance.com and reviewed and distributed by Stacker.

The post How gas prices have changed in the U.S. in the last week Jan. 5, 2026 appeared first on News Channel 3-12.

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A bathroom remodel is an excellent way to increase the value of your home and create a more enjoyable atmosphere while you live in your residence, but cost is a factor. You must budget carefully to get the results you’re looking for without breaking the bank. It’s easy to get in over your head.

However, with the right budgeting strategy, you can find the ideal balance. But how much does a bathroom remodel cost?

Bathroom remodel expenses can vary wildly depending on the extent of your renovation, the materials used, and the fixtures added. It can be difficult to assign a number to the total cost. But once you determine what you want, you can research to find out prices and create a budget suited to your needs.

World CopperSmith’s bathroom remodel cost guide will tell you everything you need to know.

Understanding Bathroom Remodeling Costs

Your bathroom remodel cost will vary depending on what’s involved. Here are some factors to consider.

What Does a Bathroom Remodel Entail?

A bathroom remodel can entail anything from a simple paint job to breaking down the walls and building a larger bathroom. Here are some common bathroom remodeling endeavors.

• New fixtures such as the sink, toilet, and cabinets: Many households replace existing fixtures when they are no longer functional or stylish. They may also update to more energy-efficient fixtures.
• New plumbing and electrical systems: Plumbing and electrical systems wear out eventually. You may also choose to update systems for a more convenient layout.
• Replacing the sink countertops: New sink countertops can significantly enhance your bathroom aesthetics.
• Adding shelves: Shelving creates more space in small bathrooms.
• Installing safety features such as grab rails: This is a common remodeling endeavor for senior family members.
• Updated lighting: Lighting is a major factor in bathrooms. You may update your lighting for better mirror views and improved navigation.
• Breaking down walls: In extreme instances, you may even break down your bathroom walls to make a smaller or larger bathroom.
• Paint job: Painting can change the entire look of your bathroom. Consider the latest colors and styles to create an updated look.
• Shower and shower doors: Stylish shower doors can improve your bathroom aesthetics. You may also consider switching out an old showerhead or renovating the tub.
• Tiles: You may choose to replace your bathroom wall tile or floor tile to update your bathroom aesthetics. Tiles often get cracked and chipped, and grout can dull and darken. Switch them out to create a clean, modern interior design.
• New windows: Bathrooms don’t typically have many windows, but you may need to replace yours if they interfere with remodeling needs.
• Permits: Your bathroom remodel may require a permit. This will likely be the case if you update the plumbing or